Organic lead salts
Apexbio Technology LLC Irinotecan HCl Trihydrate(Synonyms: Campto, Camptosar, CPT-11, Irinotecan hydrochloride trihydrate, Irinotecan hydrochloride, Irinotecan HCl, Irinotecan, CPT 11 hydrochloride trihydrate), 10mM (in 1mL DMSO), CAS: 136572-09-3.
Irinotecan HCl Trihydrate (CAS 136572-09-3) also known as CPT-11 is a semisynthetic derivative of camptothecin designed to improve therapeutic efficacy while reducing toxicity It acts as a soluble prodrug which undergoes enzymatic cleavage by carboxylesterases in vivo to yield SN-38 a potent inhibitor of topoisomerase I CPT-11 exhibits cytotoxicity against leukemia (P388) cell lines with an IC50 of 3 4 M and demonstrates antitumor activity in vitro and in vivo against both drug-sensitive and multidrug-resistant tumor models It is FDA-approved for treating metastatic colorectal cancer following progression after fluorouracil-based therapies
Selleck Chemical LLC Irinotecan HCl Trihydrate S2217-100mg
Irinotecan HCl Trihydrate is a hydrochloride trihydrate of irinotecan (Camptosar Campto CPT-11) which is a topoisomerase I inhibitor with IC50 of 15 8 and 5 17 M for LoVo cells and HT-29 cells respectively
Medchemexpress LLC Meta-Hoechst trihydrochloride | 2320308-12-9 | 99.2% | 533.88 g·mol⁻¹ | C25H27Cl3N6O | 10 MG
HOE-S 785026 trihydrochloride is a blue fluorescent DNA nuclear stain supplied as a solid. It binds to the minor groove of double-stranded DNA and is used for nuclear staining in fluorescence microscopy and cell-based assays. Available in multiple pack sizes and high purity for research applications.
- Blue fluorescent dye suitable for DNA/nuclear staining.
- Binds the minor groove of double-stranded DNA for reliable nuclear labeling.
- High purity for reproducible experimental results.
- Available in small quantities to support assay development and optimization.
- Compatible with fluorescence microscopy and cell-based assays.
Selleck Chemical LLC Scopolamine HBr trihydrate
Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55 3 nM
Selleck Chemical LLC Magnesium lactate trihydrate S4829-25mg
Magnesium lactate the magnesium salt of lactic acid is a mineral supplement that is added to some food and beverages as an acidity regulator
Apexbio Technology LLC Peramivir Trihydrate 1041434-82-5 50mg
Peramivir Trihydrate (CAS 1041434-82-5) is a small-molecule inhibitor targeting influenza viral neuraminidase It is designed to inhibit neuraminidase activity thereby impeding viral particle release and the spread of infection Peramivir Trihydrate exerts its biological activity primarily through competitive inhibition of neuraminidase as a transition-state analog In experimental studies Peramivir Trihydrate demonstrates neuraminidase inhibitory activity with an IC50 of approximately 0 09 nM Based on these pharmacological properties Peramivir Trihydrate holds research potential in investigating influenza virus replication antiviral efficacy and neuraminidase-mediated viral dissemination
Selleck Chemical LLC Peramivir Trihydrate S2716-5mg
Peramivir Trihydrate (BCX-1812 RWJ-270201 S-021812) is a trihydrate of the anti-infection agent peramivir which is a transition-state analogue and a potent specific influenza viral neuraminidase inhibitor with an IC50 of median 0 09 nM
Sigma Aldrich Fine Chemicals Biosciences Meropenem trihydrate 98 HP50MG
Meropenem trihydrate (MRP) belongs to the carbapenem group of compounds. It is susceptible to degradation at high temperature and humidity. It is soluble in methanol-water or acetone-water combinations. It is used as an antibacterial agent for treating meningitis and pneumonia.
Selleck Chemical LLC Amifostine trihydrate S4298-50mg
Amifostine trihydrate(WR2721 trihydrate) is the first approved radioprotective drug used to decrease the risk of kidney problems caused by treatment with cisplatin
Apexbio Technology LLC Vardenafil HCl Trihydrate 330808-88-3 10mM (in 1mL DMSO)
Vardenafil HCl Trihydrate (CAS 330808-88-3) is the trihydrate salt form of vardenafil a potent and selective inhibitor of phosphodiesterase type 5 (PDE5) In enzymatic assays vardenafil demonstrates an IC50 of 0 7 nM for PDE5 exhibiting high selectivity over other phosphodiesterase isoforms with significantly higher IC50 values for PDE1 PDE2 PDE3 PDE4 and PDE6 Vardenafil enhances relaxation of human trabecular smooth muscle in response to sodium nitroprusside acetylcholine and electrical stimulation and increases cGMP concentrations in human corpus cavernosum tissue These properties establish its utility in studies addressing cGMP-mediated smooth muscle relaxation and PDE5-related pharmacology
TARGETMOL CHEMICALS INC Peramivir Trihydrate 10MG
Also available in 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes.Peramivir Trihydrate (RWJ-270201) is a neuraminidase inhibitor (IC50 0.09 nM) which prevents normal processing of virus particles such that virus particles are not released from infected cells. Peramivir Trihydrate is a cyclopentane derivative with activity against influenza A and B viruses. Purity 99.6%
Selleck Chemical LLC Magnesium lactate trihydrate S4829-1g
Magnesium lactate the magnesium salt of lactic acid is a mineral supplement that is added to some food and beverages as an acidity regulator
Medchemexpress LLC Cefixime (trihydrate) | 125110-14-7 | 99.8% | 507.50 g·mol⁻¹ | C16H21N5O10S2 | 10 MG
Cefixime trihydrate is a third-generation cephalosporin antibiotic used as a research reagent and analytical standard for studying antibacterial activity and for analytical testing.
- Third-generation cephalosporin antibiotic.
- High purity analytical standard (COA example 99.77%).
- White to off-white solid, easily handled in laboratory settings.
- Molecular weight 507.50 g·mol⁻¹; molecular formula C16H21N5O10S2.
- CAS number 125110-14-7 for unambiguous identification.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3901720 SODIUM ACETATE TRIHYDRATE 1KG